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Researchers at the Department of Nutrition and Dietetics at King’s College London report that low GI meals increased the levels of GLP-1 gut hormone levels, leading to the suppression of appetite and the feeling of fullness in a paper presented at the annual society for endocrinology BES meeting in the UK in March 2009.

Dr Tony Leeds, and Reza Norouzy looked at the effects of a single low versus high GI meal on gut hormone levels in 12 healthy volunteers. Each participant ate an identical moderate GI meal for dinner, fasted overnight, and was given either a low GI (46) or high GI (66) meal for breakfast. Blood samples were then taken every 30 minutes for 150 minutes, and levels of the gut hormone GLP-1 and insulin measured. GLP-1 is a hormone produced by the gut that has been shown to cause a feeling of fullness and suppression of appetite. Volunteers who ate a low GI breakfast had 20% higher blood plasma levels of GLP-1 and 38% lower levels of insulin compared to those who had consumed a high GI breakfast.

Researcher Dr Reza Norouzy said: ‘Our results suggest that low GI meals lead to a feeling of fullness because of increased levels of GLP-1 in the bloodstream. We now need to expand the findings of this preliminary study and look at the effects of low versus high GI meals in a larger group of people.’
– Kings College London press release.

For a super online database of foods with a GI index rating, take a look here